500bb out of position: the 4-bet range is a keep, the call range is a watchlist, and folding is a skill.
4-betting narrows to the very top; suited hands with nut potential call more. The question on every street becomes: which hands are happy getting 500bb in?
You raised the small blind, the big blind 3-bet with position. Every postflop street will be played at a disadvantage — plan accordingly.
Assumes a standard 3-bet; 4-bet to ~2.2–2.5x the 3-bet. Deep, favor calls over 4-bets — a 4-bet pot at 500bb+ commits you with range disadvantage.