The super-deep shape: pairs, suited aces, connected suited hands, AKo — and nothing that wins a big pot only when it is beaten.
Only hands that can make the nuts — or fold without regret — belong in the range. Offsuit big cards win small pots and lose enormous ones.
Middle position opens are still into five or six players. The range grows from EP, but the same discipline about dominated offsuit hands applies.
Assumes a live-standard open to ~4bb, raise-or-fold. In straddled games, halve your effective big blinds and read the chart at that depth.